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NMO-IgG/ AQP4 Autoantibodies

NMO-IgG/ aquaporin-4

Anti-Aquaporin-4 IIFT: transfected cells (top), non-transfected cells (bottom)

  • Screening test for detection of antibodies against aquaporin-4(AQP4)/NMO-IgG.
  • Indication: neuromyelitis optica.
  • Antibodies against aquaporin-4 (NMO-IgG) cause fluorescence of the small cerebral vessels, the pia, the subpia and the Virchow-Robin space on the optical nerve and cerebellum tissue substrates. Aquaporin-4(AQP4) transfected HEK cells enable monospecific antibody detection in suspected cases of neuromyelitis optica (NMO).

Technical info and Images credit to EUROIMMUN AG