Calprotectin is produced by neutrophil granulocytes and monocytes. In the case of an inflammatory disease of the intestine, granulocytes pass into the intestinal lumen and release calprotectin which is then excreted with the stool. The concentration of calprotectin in stool is therefore an indicator for the severity of an inflammatory process in the intestine. Hence, this non-invasive stool test enables:
Technical info and Images credit to EUROIMMUN AG